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Methoxyflurane: Chemical Structure, Mechanism of Action, Uses & Side Effects

sachinkumar244

Chemical Structure:

  • C3H4Cl2F2O

Chemical Structure
Chemical Structure

Mechanism of Action:

  • Neurotransmitter Modulation: It likely modifies the transmission of signals in the central nervous system, similar to other inhalational anesthetics. This involves both the enhancement of inhibitory pathways and the reduction of excitatory neurotransmission.

  • Ion Channel Influence: Affects the activity of various ion channels, which alters the excitability of nerve cells.

Uses:

  • Pain Management: Mainly used for its analgesic properties in emergency settings, especially for acute trauma.

  • Anesthesia: Historically used in anesthesia but is now less common due to its side effects.

Side Effects:

  • Nephrotoxicity: Particularly notable with this agent, as it can lead to significant kidney damage.

  • Respiratory Depression: Common with anesthetics; it reduces the drive to breathe.

  • Cardiovascular Effects: Can cause hypotension.

  • Carcinogenic Potential: There's some concern about its potential to cause cancer.

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