Moxifloxacin: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Formula:

• C21H24FN3O4

Structure of Moxifloxacin

Mechanism of Action:

• Moxifloxacin is also a fourth-generation fluoroquinolone antibiotic.

• Like gatifloxacin, it inhibits bacterial DNA gyrase and topoisomerase IV, which are responsible for DNA replication, transcription, and repair.

• This inhibition leads to bacterial cell death.

Uses:

Moxifloxacin is used to treat a variety of bacterial infections, such as:

• Acute bacterial sinusitis

• Acute bacterial exacerbation of chronic bronchitis

• Community-acquired pneumonia

• Complicated skin and skin structure infections

• Complicated intra-abdominal infections

Side Effects:

Some common side effects of moxifloxacin include:

• Nausea

• Diarrhea

• Headache

• Dizziness

• Abdominal pain

• Vomiting

Serious side effects may include:

• Tendon rupture or inflammation

• Peripheral neuropathy

• Central nervous system effects (e.g., seizures, anxiety, depression)

• Photosensitivity

• Hypersensitivity reactions

• QT interval prolongation

• Clostridium difficile-associated diarrhea