Naftifine Hydrochloride
- BP-S-6-Medicinal Chemistry III
- 3 days ago
- 1 min read
Chemical Structure / Formula of Naftifine Hydrochloride
Formula: C21H21N · HCl
Structure: Allylamine antifungal with a naphthalene core.

Mechanism of Action
Inhibits squalene epoxidase, blocking ergosterol synthesis and leading to toxic squalene accumulation.
Uses
Topical antifungal (tinea infections, athlete’s foot, jock itch, ringworm).
Side Effects
Skin irritation, redness, burning.