Chemical formula:
C12H12N2O3
![Structure of Nalidixic](https://static.wixstatic.com/media/c7082f_92062188957f48889c5693ce51f09f8f~mv2.png/v1/fill/w_980,h_750,al_c,q_90,usm_0.66_1.00_0.01,enc_auto/c7082f_92062188957f48889c5693ce51f09f8f~mv2.png)
Mechanism of action:
Nalidixic acid inhibits bacterial DNA replication by targeting DNA gyrase (topoisomerase II) and topoisomerase IV, preventing the unwinding of DNA and subsequent replication.
Uses:
Nalidixic acid is primarily used to treat uncomplicated lower urinary tract infections caused by susceptible Gram-negative bacteria.
Side effects:
Side effects can include gastrointestinal disturbances, hypersensitivity reactions, central nervous system (CNS) effects (e.g., headache, dizziness), and phototoxicity.