Nandrolone is an androgen and anabolic steroid also known as 19-nortestosterone.
Similar to testosterone.
Structure
Nandrolone (Androlone-D) Chemical Structure –
Mode of action
Its mechanism of action is similar as the testosterone, bit it has a greater ability to binds with androgen receptor.
Nandrolone interacts with the androgen receptor when it enters cells through receptor-mediated endocytosis.
A conformational change occurs after interaction to the androgen receptor.
To control transcription, the androgen receptor enters the nucleus, dimerizes, and then binds to certain DNA sequence.
Uses
It is used to treat
Osteoporosis
Breast cancer
Cancer
AIDS
Enhanced bone density
Muscular growth
Anaemia.