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Naringin: Occurrence, Chemical Nature, Medicinal Benefits

  • A flavonoid found predominantly in grapefruit and other citrus fruits.

  • Naringin enhances the antioxidant capacity of the body, helps in lipid metabolism which may contribute to weight loss, and has been shown to improve blood glucose control.

Occurrence:

  • Naringin is predominantly found in grapefruits and other citrus fruits such as oranges and lemons.

  • It is responsible for the bitter taste observed in grapefruits.

Chemical Nature:

  • Naringin is a flavanone glycoside, consisting of the aglycone naringenin linked through a glycosidic bond to a sugar molecule.

  • It is known for its strong antioxidant capacity and other health-promoting properties.

  • The compound exhibits various biological activities, including antioxidant, anti-inflammatory, and lipid-lowering effects.

Medicinal Benefits:

1. Cholesterol Management:

  • Naringin has been shown to improve lipid metabolism, thereby helping to lower cholesterol levels in the blood.

2. Antioxidant and Anti-inflammatory:

  • Its antioxidant properties help in preventing cellular damage due to oxidative stress, and its anti-inflammatory effects can contribute to reducing inflammation throughout the body.

3. Metabolic Syndrome:

  • Studies suggest that naringin might have therapeutic potential in managing obesity, diabetes, and hypertension, components of metabolic syndrome.

4. Enhancing Drug Efficacy:

  • Naringin can affect drug metabolism and increase the bioavailability of certain medications, making them more effective.


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