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Ornidazole: Chemical Structure, Mechanism of Action, Uses & Side effects

1 min read

Chemical formula:

  • C7H10ClN3O3

Structure of Ornidazole
Structure of Ornidazole

Mechanism of action:

  • Ornidazole is another nitroimidazole derivative with a similar mechanism of action to metronidazole. It is selectively taken up by anaerobic organisms and protozoa, where it undergoes a reduction reaction, forming toxic intermediates that damage DNA structure and inhibit nucleic acid synthesis, leading to cell death.

Uses:

  • Ornidazole is used to treat various infections caused by anaerobic bacteria and protozoa, such as giardiasis, amoebic dysentery, and bacterial vaginosis.

Side effects:

  • Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), headache, dizziness, and metallic taste. In rare cases, it may cause peripheral neuropathy or seizures.


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