Ornidazole: Chemical Structure, Mechanism of Action, Uses & Side effects

Chemical formula:

• C7H10ClN3O3

Structure of Ornidazole

Mechanism of action:

• Ornidazole is another nitroimidazole derivative with a similar mechanism of action to metronidazole. It is selectively taken up by anaerobic organisms and protozoa, where it undergoes a reduction reaction, forming toxic intermediates that damage DNA structure and inhibit nucleic acid synthesis, leading to cell death.

Uses:

• Ornidazole is used to treat various infections caused by anaerobic bacteria and protozoa, such as giardiasis, amoebic dysentery, and bacterial vaginosis.

Side effects:

• Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), headache, dizziness, and metallic taste. In rare cases, it may cause peripheral neuropathy or seizures.