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Paramethadione: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure:

  • C12H14N2O3

Chemical Structure
Chemical Structure

Mechanism of Action:

  • Paramethadione works similarly to trimethadione, by reducing T-type calcium currents of the thalamic neurons.

Uses:

  • It's used to control absence seizures.

Side Effects:

  • It can cause gastrointestinal disturbances, drowsiness, and, in more serious cases, aplastic anemia.

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