Pentamidine Isethionate
- BP-S-6-Medicinal Chemistry III
- Apr 3
- 1 min read
Chemical Structure / Formula of Pentamidine Isethionate
Formula: C19H24N4O2 · C2H6O4S
Structure: Aromatic diamidine with an isethionate salt.
Mechanism of Action
Binds to DNA and inhibits RNA synthesis in protozoa.
Disrupts mitochondrial function.
Uses
Pneumocystis jirovecii pneumonia (PCP) in HIV/AIDS patients.
Trypanosomiasis (African sleeping sickness).
Side Effects
Nephrotoxicity, hypotension, pancreatitis.
