Pentazocine: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure:

• C19H27NO

Chemical Structure

Mechanism of Action:

• Acts as a kappa-opioid receptor agonist and a partial agonist or antagonist at mu-opioid receptors. This mixed activity can lead to less respiratory depression and a lower risk of dependence compared to full mu-opioid agonists.

Uses:

• Moderate to Severe Pain: Often used in settings where the use of stronger opioids is to be avoided.

Side Effects:

• Psychotomimetic Effects: Including hallucinations and confusion, particularly at higher doses.

• Less Respiratory Depression: Compared to full mu-agonists, but still present.

• Withdrawal Syndrome: If used after or with other full mu-opioid agonists.