Permeation through skin

• Permeation through skin refers to the process by which substances pass through the outermost layer of the skin (epidermis) and enter the bloodstream or underlying tissues.

• This can occur with chemicals, drugs, or other agents, and is the basis for treatments like transdermal patches.

• Factors affecting permeation include the substance's size, solubility, and the condition of the skin.

Illustration of Application of TDDS

• Anatomy of skin: Layers, Accessory Structures, Sensory Receptors, Specialized Cells & Functions

• Mechanism of drug transport across the skin

• Layers of Skin involved in drug transport & Routes of Skin Penetration