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Piperocaine

Structure

  • Piperocaine is a synthetic local anesthetic with a piperidine ring attached to a benzamide core, enhancing its anesthetic potency and duration.

  • Chemical Formula: C₁₀H₂₁N₃O

    formula of Piperocaine
Structure of Piperocaine
Structure of Piperocaine

Mode of Action

  • Sodium Channel Inhibition: Blocks voltage-gated sodium channels, preventing nerve impulse propagation.            

  • Enhanced Potency: More potent than benzocaine due to structural modifications.

Uses

  • Dental Anesthesia: Employed in dental procedures for effective local numbing.

  • Ophthalmic Procedures: Used in eye surgeries for corneal anesthesia.

  • Minor Surgical Procedures: Applied in small-scale surgical interventions requiring local anesthesia.

Side Effects

  • Central Nervous System Effects: Dizziness, tremors, and in severe cases, seizures.

  • Cardiovascular Toxicity: Hypotension and arrhythmias with high doses.


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