top of page
Search

Pralidoxime Chloride: Chemical Structure, Mechanism of Action, Uses & Side Effects

sachinkumar244
1 min read

Chemical Structure:

  • C7H9ClN2O

Chemical Structure
Chemical Structure

Mechanism of Action:

  • Pralidoxime chloride is a cholinesterase reactivator. It works by binding to the organophosphate-inhibited acetylcholinesterase enzyme and breaks the phosphorus-enzyme bond.

  • This reactivates the enzyme and allows it to resume its role in breaking down acetylcholine in the synaptic cleft.

Uses:

  • It is used as an antidote for organophosphate poisoning (such as from certain pesticides and nerve gases), which can cause severe muscle weakness and potentially fatal respiratory failure.

Side Effects:

  • Side effects may include blurred vision, double vision, difficulty swallowing, dizziness, headache, drowsiness, nausea, stomach pain, nervousness, restlessness, rapid heartbeat, and hives or rash.

  • In rare cases, it can cause high blood pressure and pulmonary edema.



bottom of page