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Prazosin: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure/Formula:

  • C19H21N5O4

Structure of Prazosin
Structure of Prazosin

Mechanism of Action:

  • Prazosin is a selective alpha-1 adrenergic receptor antagonist. It relaxes vascular smooth muscles, leading to vasodilation and a decrease in blood pressure.

Uses:

  • Prazosin is primarily used to treat hypertension. It's also used in the treatment of benign prostatic hyperplasia (BPH) and as an off-label treatment for PTSD-related nightmares.

Side Effects:

  • Common side effects include dizziness, headache, drowsiness, lack of energy, weakness, palpitations, and nausea. It may also cause a sudden drop in blood pressure upon standing (postural hypotension).

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