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Preparation of Ointments

  • Ointments are semi-solid preparations used topically on the skin or mucous membranes to provide a protective, soothing, or therapeutic effect.

  • They are typically composed of an oily or greasy base, which helps to retain moisture, and may contain active ingredients to treat various conditions or ailments.

  • Ointments are widely used in dermatology, wound care, and other medical applications.

Preparation:

  • Ointments can be prepared using various methods, with the most common being fusion, levigation, and incorporation.

1. Fusion:

  • This involves melting the ingredients together, with the base being heated first, followed by the addition of other ingredients.

  • Once the mixture is homogeneous, it is allowed to cool and solidify.

  • This method is used for preparing ointments with components that need to be melted together.

2. Levigation:

  • This involves triturating (grinding) a solid ingredient into a fine powder and then mixing it with the ointment base.

  • The fine powder ensures that the active ingredient is evenly distributed throughout the ointment.

Types:

Ointments can be broadly classified into four main types, based on their base composition:

  1. Oleaginous (oil-based) ointments

  2. Absorption ointments

  3. Water-removable (water-washable) ointments

  4. Water-soluble ointments

Uses:

Ointments have a wide range of uses, including:

  1. Protection

  2. Moisturization

  3. Wound care

  4. Pain relief

  5. Antifungal and antiviral treatments


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