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Preparation of Pastes

Definition

  • Pastes are semi-solid topical preparations containing a high proportion of solid substances dispersed in a base.

  • They are thicker and stiffer than ointments, allowing them to adhere to the skin for extended periods.

  • Pastes are used to protect, soothe, and provide localized effects.

Preparation Methods

Preparation Methods
  1. Levigation

    • Solid ingredients are ground into fine powder and then mixed with the paste base to ensure even distribution of the active ingredient.

  2. Incorporation

    • Ingredients are mixed together using a mortar and pestle or similar equipment until a homogenous mixture is achieved.

    • The base typically consists of fatty substances like petrolatum and solid ingredients such as zinc oxide or starch.

  3. Fusion

    • Ingredients are melted together, then cooled to form a solid paste.

    • This method is less common but used when components need to be melted.

Types of Pastes

  1. Fatty pastes

  2. Absorptive pastes

  3. Emulsion pastes

Uses

  • Pastes are used for:

    • Protection

    • Absorption

    • Wound care

    • Antipruritic and anti-inflammatory effects

    • Antifungal and antibacterial treatments


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