Properties of Polymers
Biocompatibility:
Should not provoke an immune response.
Essential for safety and efficacy.
Mechanical Strength:
Must withstand physiological conditions without disintegrating prematurely.
Permeability:
Controls the rate at which the drug diffuses through the polymer.
Degradability:
Rate of degradation can be tailored to match the desired drug release profile.
Solubility and Swelling:
Hydrophilic polymers may swell, affecting drug release kinetics.
Applications of Polymer
Matrix Tablets:
Drug is embedded within a polymer matrix.
Release occurs through diffusion and/or erosion of the matrix.
Coated Dosage Forms:
Polymers are used as coatings to control the dissolution rate of the tablet or capsule.
Microspheres and Nanoparticles:
Polymers form tiny particles that encapsulate the drug.
Suitable for injectable controlled release systems.
Transdermal Patches:
Polymers act as the adhesive matrix controlling drug release through the skin.
Implantable Devices:
Polymers used in implants provide long-term therapy without the need for frequent dosing.
Hydrogels:
Cross-linked polymer networks that can swell and control drug releases
Above are all the main Properties & Applications of Polymers