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Propoxyphene Hydrochloride: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure:

  • C22H29NO2 · HCl

Chemical Structure
Chemical Structure

Mechanism of Action:

  • A mild to moderate mu-opioid receptor agonist.

Uses:

  • Historically used for mild to moderate pain relief, but its use has significantly declined due to safety concerns and has been withdrawn from the market in many countries.

Side Effects:

  • Cardiotoxicity: Significant risk, including fatal arrhythmias.

  • CNS Depression: Drowsiness, dizziness, and sedation.

  • GI Effects: Nausea and constipation.

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