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Pyridostigmine: Chemical Structure, Mechanism of Action, Uses, Side Effects

sachinkumar244
1 min read

Chemical Structure:

  • C9H13N3O2

Chemical Structure
Chemical Structure

Mechanism of Action:

  • Pyridostigmine is also a quaternary ammonium compound. It inhibits acetylcholinesterase at the neuromuscular junction, increasing the concentration of acetylcholine and thereby enhancing neuromuscular transmission.

Uses:

  • It is primarily used to treat myasthenia gravis and has been used as a prophylactic agent against nerve agents in chemical warfare.

Side Effects:

  • Side effects include nausea, diarrhea, abdominal cramps, increased salivation and sweating, and muscle twitching. Overdose can lead to a cholinergic crisis.

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