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Reduction

Definition of Reduction:

  • Reduction is the gain of electrons or loss of oxygen, often resulting in undesirable changes in drug activity or color.

Examples:

Example Reaction (Reduction of Nitro Compounds):

Example Reaction (Reduction of Nitro Compounds)

Example Reaction (Reduction of Ketones to Alcohols):

Example Reaction (Reduction of Ketones to Alcohols)

Prevention Strategies:

  • Incorporate antioxidants or reducing agents.

  • Maintain appropriate pH to minimize reactions.

  • Use stabilizers and light-resistant packaging


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Polymorphism

Definition of polymorphism : The ability of a drug substance to exist in multiple crystalline forms  with different arrangements or...

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