Rifabutin
- BP-S-6-Medicinal Chemistry III
- Mar 29
- 1 min read
Chemical Structure / Formula of Rifabutin
Formula: C46H62N4O11
Structure: Similar to rifampicin but with less CYP450 induction.
Mechanism of Action
Inhibits bacterial RNA polymerase, preventing mRNA synthesis.
Uses
TB treatment in HIV patients (less interaction with antiretrovirals).
Side Effects
GI upset, myalgia, uveitis.
