Ruta (Flavonoids)

Introduction to Ruta (Flavonoids)

• Ruta, primarily Ruta graveolens (Rue), is rich in flavonoids and exhibits anti-inflammatory, antispasmodic, and antimicrobial properties.

Illustration of Ruta (Flavonoids)

Synonyms

• Common name: Rue

• Scientific name: Ruta graveolens

• Other names: Herb-of-grace, Common rue

Biological Source

• Derived from the aerial parts (leaves and stems) of Ruta graveolens.

Family

• Rutaceae

Composition

• Major flavonoids:

  • Rutin (quercetin glycoside)

  • Quercetin

  • Hesperidin

  • Apigenin

Chemistry:

• Class: Flavonoids (flavonols and flavones).

• Structure:

  • Rutin: Glycoside of quercetin with sugar moieties.

  • Quercetin: A polyhydroxy flavonoid with antioxidant activity.

• Solubility: Water-soluble due to glycosidic linkages.

Therapeutic Uses:

• Antioxidant: Rutin and quercetin combat oxidative stress.

• Capillary Strengthening: Rutin enhances capillary resistance, aiding conditions like varicose veins and hemorrhoids.

• Anti-inflammatory: Rutin and hesperidin inhibit inflammatory pathways.

• Antispasmodic: Relaxes smooth muscles, alleviating gastrointestinal and uterine spasms.

• Antimicrobial: Effective against various bacteria and fungi.

Commercial Applications:

• Rutin supplements: For vascular health (varicose veins, hemorrhoids).

• Herbal teas/tinctures: Used for antispasmodic and sedative effects.

• Cosmetics: Rutin and quercetin in anti-aging and skin-lightening products.