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Sample Handling Techniques in Infrared (IR) Spectroscopy

  • Proper sample preparation is essential for obtaining accurate IR spectra.

  • Techniques vary based on the sample's physical state: solid, liquid, gas, or solution.

1) Solid Sampling:

a) KBr Pellet Technique:

  • Solid is ground with potassium bromide (transparent to IR) and pressed into a pellet.

b) Mull Technique:

  • Solid is mixed with mineral oil to form a mull, then spread between NaCl salt plates.

c) Diffuse Reflectance (DRIFT):

  • Used for solids unsuitable for other methods. The sample is mixed with a reflective medium, and the reflected IR radiation is analyzed.

2) Liquid Sampling:

a) Thin Film:

  • A thin liquid film is placed between NaCl plates for analysis, suitable for non-corrosive liquids.

b) Solution Technique:

  • Sample dissolved in an IR-transparent solvent and analyzed in a liquid cell or between salt plates.

3) Gas Sampling:

a) Gas Cells:

  • Special cells with salt windows and variable path lengths are used. The gas is sealed in the cell for analysis.

4) Solution Sampling:

a) Salt Plates:

  • A drop of solution is placed between plates. After solvent evaporation, the remaining solute is analyzed.

b) Liquid Cells:

  • Two salt plates, separated by a thin spacer, form a liquid cell. The solution is added for spectrum measurement.


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