Sevoflurane: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure:

• C4H3F7O

Chemical Structure

Mechanism of Action:

• GABA and Glycine Potentiation: Enhances the effects of inhibitory neurotransmitters.

• Neuronal Excitability Reduction: Alters ion channels, leading to a decrease in the excitability of neurons.

Uses:

• Anesthesia Induction and Maintenance: Particularly favored for its rapid onset and recovery, making it ideal for both induction and maintenance of anesthesia.

• Pediatric Anesthesia: Its mild odor and less irritating properties make it suitable for use in children.

Side Effects:

• Respiratory Depression: Can decrease respiratory drive.

• Hypotension: May cause a drop in blood pressure.

• Cerebral Effects: Can cause a transient increase in cerebral blood flow, which might be a concern in patients with intracranial pathology.