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Sodium Salicylate: Chemical Structure, Mechanism of Action, Uses, Side Effects

Chemical Structure:

  • C7H5NaO3

Chemical Structure
Chemical Structure

Mechanism of Action:

  • Sodium salicylate inhibits cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins and thromboxanes. This inhibition reduces inflammation, pain, and fever. It also interferes with the production of protective mucus in the stomach, increasing the risk of gastrointestinal irritation.

Uses:

  • It's used for pain relief, as an anti-inflammatory agent, and for fever reduction. It's also utilized in the treatment of rheumatic fever and rheumatoid arthritis.

Side Effects:

  • Common side effects include gastrointestinal irritation and increased bleeding risk. In high doses, it can cause tinnitus. There's a risk of Reye's syndrome in children and teenagers recovering from viral infections.

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