Structure
Sotalol Chemical Structure – C12H20N2O3S
Mode of action
Sotalol inhibits the fast potassium channel competitively.
The duration of action potentials and the refractory period in the atria and ventricles are both increased by this inhibition.
As heart rate decreases, the inhibition of rapid potassium channels increases.
Uses
Ventricular arrhythmias are treated with sotalol.
It has some beta blocker activity.
Also used in hypertension and myocardial infarction.