Streptomycin: Chemical Structure, Mechanism of Action, Use & Side effects

Chemical formula:

• C21H39N7O12

Structure of Streptomycin

Mechanism of action:

• Binds to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis.

Use:

• Primarily used for tuberculosis and endocarditis.

Side effects:

• Nephrotoxicity (kidney damage), ototoxicity (damage to the ear, particularly the cochlea or auditory nerve), hypersensitivity reactions.

Example:

• Generic drug used in combination therapy for tuberculosis.