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Sulfasalazine: Chemical Structure, Mechanism of Action & Uses

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Chemical formula:

  • C18H14N4O5S

Structure of Sulfasalazine
Structure of Sulfasalazine

Mechanism of action:

  • Sulfasalazine is a prodrug that is cleaved in the colon by bacteria into two active components, sulfapyridine and 5-aminosalicylic acid. The mechanism of action is not completely understood, but it is believed to involve the inhibition of prostaglandin synthesis and other inflammatory mediators.

Uses:

  • Sulfasalazine is used for the treatment

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