Sulfisoxazole: Chemical Structure, Mechanism of action, Uses, Side effects

Chemical formula:

• C11H13N3O3S

Structure of Sulfisoxazole

Mechanism of action:

• Sulfisoxazole inhibits bacterial dihydropteroate synthase, blocking the synthesis of folate and leading to bacterial cell death.

Uses:

• Sulfisoxazole is used to treat a variety of bacterial infections, including urinary tract infections, respiratory infections, and ear infections. It is also used in combination with erythromycin for the treatment of otitis media.

Side effects:

• Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), rash, and hypersensitivity reactions. Rarely, it may cause blood dyscrasias, kidney disorders like crystalluria or interstitial nephritis, and liver toxicity.