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Sulphamethizine: Chemical Structure, Mechanism of Action, Uses & Side effects

Chemical formula:

  • C12H14N4O2S

Structure of Sulphamethizine
Structure of Sulphamethizine

Mechanism of action:

  • Sulphamethizine inhibits bacterial dihydropteroate synthase, blocking the synthesis of folate and leading to bacterial cell death.

Uses:

  • Sulphamethizine is used to treat various bacterial infections, including urinary tract infections, respiratory infections, and skin infections.

Side effects:

  • Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), rash, and hypersensitivity reactions. Rarely, it may cause blood dyscrasias, kidney disorders like crystalluria or interstitial nephritis, and liver toxicity.

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