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Sulphapyridine: Chemical Structure, Mechanism of Action, Uses & Side effects

sachinkumar244
1 min read

Chemical formula:

  • C11H11N3O2S

Structure of Sulphapyridine
Structure of Sulphapyridine

Mechanism of action:

  • Sulphapyridine inhibits bacterial dihydropteroate synthase, blocking the synthesis of folate and leading to bacterial cell death.

Uses:

  • Sulphapyridine is now rarely used as an antibacterial agent due to its side effects and the availability of more effective alternatives. It was once used to treat various bacterial infections, including urinary tract infections, respiratory infections, and meningitis.

Side effects:

  • Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), rash, and hypersensitivity reactions. Rarely, it may cause blood dyscrasias, kidney disorders like crystalluria or interstitial nephritis, and liver toxicity.

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