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Diallyl Sulfides: Occurrence, Chemical Nature and Medicinal Benefits

  • These are sulfur-containing compounds found in garlic and onions.

  • They have multiple health benefits including enhancing cardiovascular health by improving blood lipid profiles and reducing blood pressure.

  • These compounds also have anticancer properties, potentially inhibiting the growth of various types of cancer cells.

  • Moreover, they boost the immune system by promoting the activity of certain immune cells.

Occurrence:

  • Diallyl sulfides are primarily found in garlic and, to a lesser extent, in other members of the Allium family.

  • They are responsible for the distinctive smell and flavor of garlic.

Chemical Nature:

  • Diallyl sulfides are organic sulfur compounds characterized by the presence of two allyl groups attached to a sulfur atom.

  • They belong to a broader class of sulfur-containing phytochemicals known as organosulfur compounds. These compounds are oil-soluble and volatile, contributing to the aroma of garlic.

Medicinal Benefits:

1. Antioxidant Properties:

  • Diallyl sulfides exhibit strong antioxidant activities, helping to neutralize free radicals and reduce oxidative stress in the body.

2. Antimicrobial Activity:

  • They possess antimicrobial properties against a wide range of microorganisms, including bacteria, fungi, and viruses, making them useful in fighting infections.

3. Cardiovascular Health:

  • Diallyl sulfides have been shown to improve cardiovascular health by reducing lipid levels in the blood, lowering blood pressure, and inhibiting platelet aggregation, thereby reducing the risk of heart disease and stroke.

4. Cancer Prevention:

  • Research suggests that diallyl sulfides may play a role in cancer prevention by inducing the detoxification of carcinogens, inhibiting cancer cell growth, and inducing apoptosis (programmed cell death) in cancer cells.


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