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Taxus (Diterpenoids)

General Introduction

  • Taxus (Yew tree) is a source of the diterpenoid paclitaxel, a potent anticancer agent.

Synonyms of Taxus

  • Common name: Yew

  • Scientific name: Taxus brevifolia, Taxus baccata

  • Synonyms: Pacific Yew, European Yew

Biological Source

Taxus (Diterpenoids) plant
Taxus (Diterpenoids)

  • Derived from the bark of Taxus brevifolia and needles of Taxus baccata.

Family

  • Taxaceae

Composition

  • Major diterpenoid:

    • Paclitaxel (Taxol): The primary active compound.

Chemistry & Chemical Classes

  • Chemical Class: Diterpenoids.

  • Structure:

    • Paclitaxel is a complex diterpenoid with a taxane skeleton.

Therapeutic Uses

  • Anticancer: Used in chemotherapy for breast, ovarian, and lung cancers.

Commercial Applications

  • Paclitaxel is marketed as Taxol in injectable formulations.


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