Thiabendazole
- BP-S-6-Medicinal Chemistry III
- Apr 3
- 1 min read
Chemical Structure / Formula of Thiabendazole
Formula: C10H7N3S
Structure: A benzimidazole derivative with a thiazole ring.
Mechanism of Action
Inhibits microtubule synthesis, disrupting worm metabolism and reproduction.
Inhibits mitochondrial fumarate reductase, affecting parasite energy production.
Uses
Strongyloidiasis, cutaneous larva migrans, Trichinosis.
Side Effects
GI upset, dizziness, hepatotoxicity.
Hypersensitivity reactions (Stevens-Johnson syndrome).
