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Thiamylal Sodium: Chemical Structure, Mechanism of Action, Uses & Side Effects

sachinkumar244
1 min read

Chemical Structure:

  • C12H17N2NaO3S

Chemical Structure
Chemical Structure

Mechanism of Action:

  • GABA Receptor Modulation: Similar to other barbiturates, thiamylal enhances the inhibitory action of GABA on the central nervous system.

  • Depressant Effect: Leads to the depression of the reticular activating system, causing sedation, hypnosis, and anesthesia.

Uses:

  • Induction of Anesthesia: Frequently used for the induction of anesthesia, particularly in surgical procedures.

  • Sedation: Sometimes used for sedation in various medical procedures.

Side Effects:

  • Respiratory Depression: Can lead to significant decreases in respiratory drive.

  • Cardiovascular Effects: Hypotension and bradycardia are common.

  • Pain on Injection: Often reported by patients.

  • Cerebral Blood Flow: May increase cerebral blood flow, which could be an issue in patients with increased intracranial pressure.

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