top of page
Search
1 min read

Tocainide hydrochloride

Structure

  • Tocainide hydrochloride is an amide-type antiarrhythmic agent structurally related to procainamide. It features a diethylaminoethyl side chain attached to a 2,6-dimethyl-p-aminobenzoic acid core.

  • Chemical Formula: C₁₀H₁₅N₃O₂S·HCl

    Chemical Formula of Tocainide hydrochloride
Structure of Tocainide hydrochloride
Structure of Tocainide hydrochloride

Mode of Action

  • Class IA Antiarrhythmic: Blocks fast sodium channels, prolongs action potential duration and refractory period.

  • Potassium Channel Blockade: Extends repolarization by inhibiting potassium efflux.

  • Effect on Heart Rate: Converts atrial fibrillation to sinus rhythm and prevents reentrant arrhythmias.

  • Faster Onset: Compared to procainamide, tocainide has a more rapid onset of action.

Uses of Tocainide hydrochloride

  • Ventricular Arrhythmias: Treats ventricular tachycardia and ventricular fibrillation.

  • Atrial Arrhythmias: Manages atrial fibrillation and atrial flutter.

  • Reentrant Arrhythmias Prevention: Effective in preventing recurrence post-cardiac events.

  • Antiarrhythmic Prophylaxis: Used after myocardial infarction to prevent arrhythmias.


Attention!  We are facing some technical difficulties from google end because of which you may see empty blank spaces in between text. Please Ignore them, that does not mean incomplete or missing content. we are working on resolving the issue.  Keep Learning from world's best exam Notes!

bottom of page