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Tolazoline: Chemical Structure, Mechanism of Action, Uses & Side Effects

sachinkumar244
1 min read

Chemical Structure/Formula:

  • C10H12N2

Structure of Tolazoline
Structure of Tolazoline

Mechanism of Action:

  • Tolazoline is a non-selective alpha-adrenergic antagonist. It works by blocking alpha-adrenergic receptors, leading to vasodilation and a decrease in blood pressure. It also has some stimulant effects on the heart.

Uses:

  • It is used primarily to reverse the effects of medications that increase blood pressure and to treat certain types of heart failure in newborns (persistent pulmonary hypertension of the newborn).

Side Effects:

  • Side effects can include headache, nausea, vomiting, dizziness, and a rapid heart rate. In some cases, it may also cause a drop in blood pressure or arrhythmias.

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