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Urinary System

Definition

  • The urinary system (renal system) removes waste, maintains electrolyte balance, regulates blood pressure, and produces hormones.

Anatomy

  • Kidneys (2): Filter blood, regulate fluid, electrolytes, acid-base balance, and produce hormones (erythropoietin, renin).

  • Ureters (2): Transport urine to the bladder via peristalsis.

  • Bladder: Stores urine (300–500 mL capacity).

  • Urethra: Excretes urine.

    • Male (20 cm): Passes through prostate.

    • Female (4 cm): Higher UTI risk.

Functions

  • Filtration and Excretion: Removes waste (urea, creatinine).

  • Balance: Regulates fluids, electrolytes, and pH.

  • Blood Pressure Regulation: Renin-angiotensin-aldosterone system (RAAS).

  • Hormone Production:

    • Erythropoietin: Stimulates RBC production.

    • Vitamin D Activation: Enhances calcium absorption.

Urine Formation:

  • Filtration: Forms filtrate.

  • Reabsorption: Recovers water, glucose, and electrolytes.

  • Secretion: Eliminates waste.

Common Disorders

1) Kidney Disorders:

  • CKD: Gradual loss of function.

  • AKI: Sudden decline in function.

  • Stones (Nephrolithiasis): Mineral deposits.

  • Glomerulonephritis: Glomerular inflammation.

  • PKD: Genetic cystic disorder.

2) Bladder Disorders:

  • UTI: Bacterial infection.

  • Interstitial Cystitis: Chronic inflammation.

  • Bladder Cancer: Abnormal growth.

  • Incontinence: Loss of control.

3) Urethral Disorders:

  • Urethritis: Inflammation, often infection-related.

  • Stricture: Narrowing causing urinary difficulty.

Symptoms

  • Painful Urination (Dysuria).

  • Blood in Urine (Hematuria).

  • Frequent Urination (Polyuria/Nocturia).

  • Reduced Output (Oliguria/Anuria).

  • Proteinuria: Indicates kidney damage.

Diagnosis

  • Urinalysis: Detects blood, protein, and infections.

  • Blood Tests: BUN, creatinine, electrolytes assess function.

  • Imaging: Ultrasound, CT, MRI identify stones or abnormalities.

  • Special Tests:

    • Cystoscopy: Bladder inspection.

    • Biopsy: Kidney tissue analysis.

Treatment

1) Medications:

  • Antibiotics: UTIs.

  • Diuretics: Fluid overload.

  • Analgesics: Pain relief.

  • Antihypertensives: BP control.

  • Erythropoietin: Stimulates RBCs.

2) Procedures and Surgery:

  • Dialysis: Blood filtration in kidney failure.

  • Lithotripsy: Breaks kidney stones.

  • Nephrectomy: Kidney removal (cancer).

  • Transplant: For end-stage failure.

Prevention

  • Stay hydrated and eat a balanced diet.

  • Avoid smoking and excess alcohol.

  • Maintain BP and blood sugar control.

  • Practice hygiene to prevent infections.

  • Routine check-ups for early detection.

Prognosis of Urinary System

  • Acute Disorders: Often reversible.

  • Chronic Conditions: May need lifelong management, dialysis, or transplant.

  • Early Detection: Improves outcomes and reduces complications.


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