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Vitamin E (Tocopherols and Tocotrienols): Function, Medical Benefits

  • Vitamin E is a fat-soluble antioxidant that exists in eight chemical forms, with alpha-tocopherol being the most active in humans.

  • Vitamin E is found naturally in vegetable oils, nuts, seeds, and green leafy vegetables.

The RRR alpha-tocopherol form of vitamin E

Function:

1. Antioxidant Protection:

  • Vitamin E primarily protects cell membranes from oxidative damage by reacting with lipid radicals produced in the lipid peroxidation chain reaction.

2. Anti-inflammatory:

  • Exhibits anti-inflammatory effects by modulating gene expression and enzyme activity involved in inflammation.

3. Immune Enhancement:

  • Supports the immune system, especially in the elderly, by protecting lymphocytes from oxidative damage.

4. Photoprotection and Skin Health:

  • Provides protection against UV-induced damage and may improve skin health by reducing inflammation and promoting wound healing.

Medical Benefits:

  • Crucial for preventing oxidative stress-related diseases, including cardiovascular diseases, certain cancers, and age-related macular degeneration.

  • Supplementation may benefit those with dietary deficiencies or increased oxidative stress, though excessive intake has not consistently shown benefits in preventing chronic diseases.


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