Voglibose

Structure

• Voglibose is an iminosugar derivative with a cyclitol backbone, structurally modified to enhance specificity for intestinal alpha-glucosidases.

• Chemical Formula: C₁₂H₂₀N₂O₈

  

Structure of Voglibose

Mode of Action

• Alpha-Glucosidase Inhibition: Specifically inhibits intestinal enzymes, delaying carbohydrate digestion.

• Postprandial Glycemic Control: Prevents rapid spikes in blood glucose after meals.

Uses

• Type 2 Diabetes Mellitus: Effective in managing postprandial hyperglycemia.

• Combination Therapy: Often combined with other antidiabetic agents for comprehensive glycemic management.

Side Effects

• Gastrointestinal Issues: Bloating, diarrhea, and flatulence due to fermentation of undigested carbohydrates.