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Zidovudine (AZT)

Chemical Structure / Formula of Zidovudine (AZT)

  • Formula: C10H13N5O4

  • Structure: A thymidine analog with an azido (-N3) group at C3.

Chemical Structure of Zidovudine (AZT)

Mechanism of Action

  • Converted to Zidovudine triphosphate in host cells.

  • Inhibits HIV reverse transcriptase, leading to premature DNA chain termination.

Uses

  • HIV/AIDS treatment (as part of HAART therapy).

  • Prevention of mother-to-child transmission of HIV (during pregnancy and delivery).

Side Effects

  • Bone marrow suppression (anemia, neutropenia).

  • Lactic acidosis, hepatotoxicity.

  • Myopathy, headache, GI upset.


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Chemical Structure / Formula of Acyclovir Formula:  C8H11N5O3 Structure:  A purine nucleoside analog (acyclic guanosine derivative) ....

 
 
 

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