Unit 1
Drug Discovery and Target Validation
NotesPDF · 422 KB
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Unit 2
Lead and Protein Structure Prediction
NotesPDF · 1.0 MB
Unit 3
Rational Drug Design and Screening
NotesPDF · 672 KB
Unit 4
Molecular Docking, QSAR
NotesPDF · 416 KB
Unit 5
QSAR, Prodrug Design and Drug Delivery
NotesPDF · 466 KB
PYQ & Important Questions
Prepare for Principles of Drug Discovery.
Previous Year Questions
PYQs for this subject will be added later.
Important Questions
Original subject-specific practice questions for revision.
- Describe the stages of drug discovery and the evidence supporting progression between them.
- Compare lead-identification approaches and common sources of selection bias.
- Discuss target relevance and selectivity in rational drug design.
- Explain docking assumptions and the need for independent validation.
- Discuss statistical validation, applicability domains and reproducibility in QSAR.
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