Pharmaceutical Analysis
notes

3.2

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Chapter 2.1

Column Chromatography

Chapter 2.2

Thin Layer Chromatography (TLC)

Chapter 2.3

Paper Chromatography (PC)

Chapter 2.4

Ion-Exchange Chromatography

Chapter 2.5

High Performance Liquid Chromatography (HPLC)

Chapter 2.6

High Performance Thin Layer Chromatography (HPTLC)

Chapter 2.7

Gas Chromatography (GC)

Chapter 2.9

Gel Filtration and Affinity Chromatography

Chapter 3.4

Amperometric Titrations

Chapter 4.1

Absorption Spectroscopy (UV Visible)

Chapter 4.2

Infrared (IR) Spectroscopy

Chapter 4.3

Fluorimetric Analysis

Chapter 4.5

Atomic Absorption Spectrometry

Chapter 4.6

Atomic Emission Spectroscopy

Practical notes PDFs

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Complete practical manual

Pharmaceutical Analysis practical notes

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Individual practicals22 PDFs

Practical 1

Amino Acids by Paper Chromatography

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Practical 2

Sulphonamides by Thin layer Chromatography

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Practical 3

pH and Solvent Effects on UV Spectra

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Practical 4

Derivative UV Spectroscopy

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Practical 5

Indicator pKa by UV Spectroscopy

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Practical 6

Conductometric Titration of a Mixed Acid

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Practical 7

Potentiometric Acid base Titration

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Practical 8

Drug Assay by Fluorimetry

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Practical 9

Fluorescence Quenching

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Practical 10

Sulphonamide Colour Assay Bratton Marshall Reaction

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Practical 11

Simultaneous UV Estimation of Two Drugs

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Practical 12

Salicylic Acid by Colorimetry

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Practical 13

Chloride and Sulphate in Calcium Gluconate by Nepheloturbidimetry

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Practical 14

Sodium and Potassium by Flame Photometry

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Practical 15

pKa by pH metric Titration

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Practical 16

Specific Rotation by Polarimetry

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Practical 17

IR Spectra of a Compound and Its Derivative

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Practical 18

HPLC Instrument Demonstration

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Practical 19

HPTLC Instrument Demonstration

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Practical 20

GC MS Instrument Demonstration

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Practical 21

DSC Thermal analysis Demonstration

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Practical 22

NMR Spectrum Interpretation

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PYQ & Important Questions

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Previous Year Questions

PYQs for this subject will be added later.

Important Questions

Original syllabus-based practice questions for revision.

  1. Distinguish quality assurance and quality control in pharmaceutical analysis.
  2. Compare chromatographic separation methods and their applications.
  3. Explain potentiometry and conductometry and their analytical limitations.
  4. Compare spectroscopic techniques by the information each provides.
  5. Discuss analytical-method specificity, precision, accuracy and robustness.
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