Pharm.D Year 5: Clinical Pharmacokinetics & Drug Monitoring notes. Clinical Pharmacokinetics and Drug Monitoring connects concentration measurements with the models used to interpret them. Timing, assumptions and patient-related variables are important study concepts.

What to revise

  • Parameters: distinguish clearance, volume and half-life.
  • Monitoring: connect sample timing with the interpretation question.
  • Variation: organise interaction, renal, hepatic and population concepts.

A quick self-check

Review a fictional classroom monitoring example for missing sampling information. List the facts needed to interpret the result without recommending a dose.

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