Clarithromycin

Chemical Structure / Formula of Clarithromycin

  • Formula: C₃₈H₆₉NO₁₃
  • Structure: A methylated derivative of erythromycin (at position 6), increasing stability.

Clarithromycin

Mechanism of Action

  • Same as erythromycin: binds to the 50S ribosome, preventing bacterial protein synthesis.

Uses of Clarithromycin

  • Respiratory infections (pneumonia, bronchitis, sinusitis).
  • pylori eradication therapy (used in triple therapy).
  • Mycobacterium avium complex (MAC) infections in HIV patients.

Side Effects

  • Similar to erythromycin (GI upset, QT prolongation, CYP3A4 inhibition).
  • Metallic taste (unique side effect).

Click Here to Watch the Best Pharma Videos

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.