Delavirdine

Chemical Structure / Formula of Delavirdine

  • Formula: C₂₂H₂₈N₆O₃
  • Structure: An NNRTI with a pyridine core.

Delavirdine

Mechanism of Action

  • Binds directly to HIV-1 reverse transcriptase, preventing DNA synthesis.

Uses of Delavirdine

  • HIV/AIDS therapy (HAART regimen, rarely used today).

Side Effects

  • Rash, hepatotoxicity.
  • GI upset, headache.
  • Inhibits CYP3A4 (drug interactions).

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