Gatifloxacin

Chemical Structure / Formula of Gatifloxacin

  • Formula: C₁₉H₂₂FN₃O₄
  • Structure: A fluoroquinolone with a methoxy (-OCH₃) group at C8.

Gatifloxacin

Mechanism of Action

  • Inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication.

Uses of Gatifloxacin

  • Respiratory and urinary tract infections.
  • Ophthalmic infections (available as eye drops).

Side Effects

  • Dysglycemia (hyper- or hypoglycemia, especially in diabetics).
  • QT prolongation, GI upset, dizziness.
  • Tendon rupture, hepatotoxicity.

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