Lomefloxacin

Chemical Structure / Formula of Lomefloxacin

  • Formula: C₁₇H₁₉F₂N₃O₃
  • Structure: A difluorinated quinolone with a piperazine ring at C7.

Lomefloxacin

Mechanism of Action

  • Inhibits DNA gyrase and topoisomerase IV, preventing bacterial replication.

Uses of Lomefloxacin

  • UTIs, prostatitis, and respiratory infections.
  • Less commonly used due to higher risk of photosensitivity.

Side Effects

  • Severe photosensitivity (more than other fluoroquinolones).
  • GI disturbances, dizziness, headache.
  • Tendon rupture, QT prolongation.

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