Sulfamethizole

Chemical Structure / Formula of Sulfamethizole

  • Formula: C₉H₁₀N₄O₂S₂
  • Structure: A thiazole-containing sulfonamide.

Sulfamethizole

Mechanism of Action

  • Inhibits dihydropteroate synthase, blocking folic acid synthesis in bacteria.
  • Bacteriostatic: prevents bacterial growth.

Uses of Sulfamethizole

  • Urinary tract infections (UTIs).
  • Respiratory infections.

Side Effects

  • Hypersensitivity reactions (rash, Stevens-Johnson syndrome).
  • Crystalluria, nephrotoxicity.

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