M.Pharm Semester 2 · Pharmacology: Principles of Drug Discovery notes. Principles of Drug Discovery connects target selection, lead finding and evaluation. A promising idea becomes stronger when its assumptions are tested rather than merely repeated.
What to revise
- Discovery: distinguish target, hit and lead concepts.
- Design: connect molecular modelling and QSAR with hypothesis generation.
- Evaluation: separate predicted properties from measured evidence.
A quick self-check
Map a fictional discovery sequence from question to lead evaluation. Add one decision and the evidence required before moving to the next stage.
Notes and study links
- Principles of Drug Discovery — M.Pharm Semester 2 notes
- Drug Discovery and Target Validation — notes PDF
- Lead and Protein Structure Prediction — notes PDF
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